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Anita Yadav

Anita Yadav

Mumbai University, India

Title: Development Of Novel Antitubercular Drugs: Current Status

Biography

Biography: Anita Yadav

Abstract

Tuberculosis (TB) is one of the most ancient diseases of mankind and has co-evolved with humans for many thousands of years. Drug-resistant TB is a continuing threat. Modern chemotherapy has significantly improved patient outcomes against drug sensitive tuberculosis. However, the rapid emergences of drug-resistant tuberculosis, together with the bacterium’s ability to persist and remain latent present a major public health challenge. To overcome this problem, research into novel anti-tuberculosis targets and drug candidates is thus of paramount importance. Recent advances in molecular tools make possible the identification of targets essential for survival and persistence whose inhibition is likely to shorten therapy. Various new drug targets and drug candidates have been recently reviewed. Currently there are a number of drug candidates in different phases of the discovery, pre-clinical and clinical development. There are also a number of ongoing trials using repurposed drugs, where different combinations and doses of drugs that are currently on the market, are being tested with a view of optimizing therapies.

                                         

Recent Publications

  1. Chaudhari R Y, Bhise S B, Yadav A S, Sonawane T (2016) QSAR, Synthesis and Docking Study of 1,4-DHP as Novel Antitubercular Agents JPRCP (6).

  2. GHODKE YOGITA DEEPAK* & YADAV ANITA SHASHIKANT (2014) Extraction And Pharmacological Screening Of Carvone And It’s Derivatives, IJPA- 3(1).

  3. YADAV ANITA * , MAGDUM C. S.  (2014) SYNTHESIS AND BIOLOGICAL ACTIVITY OF 1, 6-DIHYDROPYRIDINE DERIVATIVES. IJPA (3).

  4. Yadav Anita Shashikant and Ghodke Yogita Deepak (2013) KAJAL: COSMECEUTICAL, IJPA 2(9).