Day 2 :
Jinnah University for Women, Pakistan
Keynote: In vitro neuropharmacological screening of Ficus carica Linn. fruit for anxiolytic and antidepressant activity
Time : 10:00-10:40
Somia Gul is currently working as an eminent Faculty member at Jinnah University for Women in Pakistan. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended his/her valuable service towards the scientific community with his extensive research work.Member of Pakistan Pharmacy Council,and Life Time Member of Chemical Society of Pakistan
Rutin and polyphenol which are present in Ficus carica Linn. are responsible for antidepressant and anxiolytic effects. We have conducted the study to evaluate the antidepressant and anxiolytic effect of Ficus carica Linn. on mice and compare its effect with well-known prescribed antidepressant and anxiolytic drug Alprazolam. Three groups of mice were marked as control, reference and test. Each group comprise of 5 mice (n=5). Control group was on normal diet. Reference group was fed Alprazolam at a dose of 0.5 mg/60 kg while test group were provided two different dilution of Ficus carica Linn., one dilution is 250 mg/kg/100 ml of water and second dilution is 500 mg/kg/100 ml of water. Light/dark box method and elevated plus maze method were used to evaluate the anxiolytic effect of Ficus carica Linn. To determine the antidepressant effect of Ficus carica Linn., ‘Head Dip Method’ was used. Results were collected and observed readings and data were clearly indicating the great and pronounced antidepressant and anxiolytic effect of Ficus carica Linn. at a dose of 500 mg/kg compare with a widely prescribed drug Alprazolam for its antidepressant and anxiolytic effects. Ficus carica is well known for its numerous biological activities also found to be one of excellent distressing agent. Stress provoking several disorders could be limit using Ficus carica fruit in doses 250 mg/kg and 500 mg/kg. Ficus carica Linn. as a natural product may prove better therapeutic agent, if more study will have conducted on it. As this study is confined to the mice, there are many possibilities to have similar effect in humans but require more work on it.
- Zehra Ashraf, Somia Gul and Faazia Qaazi (2017) Development and validation of UV/Vis. Spectrophotometric method for determination of Clarithromycin. Journal of Chemical, Biological and Physical Sciences, Section A: Chemical Sciences; 7(2): 457-465.
- Maria Ayub, Somia Gul and Humera Khatoon (2017) Evaluation of hypouricemic, hypolipidemic and hepatoprotective potency of G. glabra ethanolic extract in atherogenic experimental rats model. Pakistan Journal of Medical Sciences; 33(2): S-11.
Taif University, KSA
Time : 10:40-11:20
Ahmed M A Masaad (Taif University, KSA). He has many contributions towards new drug and drug delivery system. He has membership of many scientific societies and an Editor of PSC Journal. He has published more than 20 scientific researches and has discovered new treatment for cancer of colon and skin.
The new treatment is mainly depending on mechanism of contraction of the connective tissue surrounding the venous around anus by effervescent tannin base with strong anti-bacterial, antifungal and anti-viral effect of formula. The safety of drugs was tested in rabbits, rats first and then the experiment was done in hundreds of patients under license of ethics committee of Taif University. The percentage of cure conducted was 99%, this success leads to relive of pain over millions of patients around the world and minimize the risk of surgery treatment and cost beside quick relive of disease in two to three weeks with no chance of relapse of disease again.