Pharmacogenomics and Precision Medicine

The pharmacogenomics comprises of genomic information being used to study an individual’s responses to drugs based on their genetic profile. When a gene variant is responsible for a particular drug response in a patient then based on genetics it is possible to derive clinical decisions by adjusting the dosage or choosing an alternative drug. Researchers study gene variants affecting an individual's drug response in a similar process as of assessing variants associated with diseases and disorders. Recent approaches include multigene analysis or whole-genome Single Nucleotide Polymorphism (SNP) profiles which are used in designing and developing drugs. By the application of human genomic data a new technique called precision medicine is being established, which is based on using an individual's genetic data to make a best therapeutic choice by facilitating predictions about whether a particular person will be beneficial by a particular medicine or suffer by serious side effects. Drugs are tested on a large population of people and the average response is reported. Personalized medicine acknowledges that no two patients are similar with respect to reaction towards medication.

  • Predictive prescribing
  • Toxgnostics
  • Clinomics
  • Molecular medicines
  • Drug safety

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